Co-amoxiclav (Clavulanate, Amoxicillin)

Co-Amoxiclav product description

Co-Amoxiclav is an antibacterial combination of a broad spectrum of action. That is why it is prescribed for different illnesses of the body.

The remedy is usually prescribed in such cases:

• viruses of the upper respiratory tract (including acute and chronic sinusitis, tonsillopharyngitis);
• viruses of the lower respiratory tract (including chronic bronchitis, pneumonia, empyema of the pleura); otitis;
• Urinary tract diseases (cystitis, urethritis,pyelonephritis);
• infections of the skin and soft tissues (including phlegmon, wound infection);
• dental illnesses;
• sepsis.

Co-Amoxiclav safety information

If we talk about contraindications, then there are not many of them. The drug is not allowed for persons with hepatitis or cholestatic jaundice, which were caused by the use of antibacterial agents of the penicillin group. Also, Co-Amoxiclav is not recommended for people with individual strong sensitivity to clavulanic acid and amoxicillin, and other ingredients of Co-Amoxiclav or penicillin preparations.

As for the opportunity to have this remedy during pregnancy, the effect of the Co-Amoxiclav on the damage of the fetus in the womb has not yet been revealed, which makes it possible to use it during the period of bearing and breastfeeding.

Co-Amoxiclav is normally prescribed intravenously because it is compatible with water for injection, lactated Ringer's solution, isotonic sodium chloride solution, potassium chloride solution. Less stable Co-Amoxiclav in spaces that contain glucose or dextran. The medication is forbidden to enter the body with other medical substances at once.

Exceeding the dose is not very dangerous, but taking Co-Amoxiclav in a very big dose can cause such conditions: insomnia, agitation, dizziness, in some cases convulsions. In case of an overdose, there is a possibility to carry out hemodialysis. The treatment is symptomatic in such cases.

Co-Amoxiclav side effects

Unnormal situations usually exist of a temporary nature and mild severity.

On the part of the digestive system: nausea (3%), diarrhea (4.1%), indigestion (1.6%) and vomiting (1.8%); rarely flatulence, anorexia, gastritis, glossitis, enterocolitis, stomatitis or discoloration of the tongue. During or after the abolition of Co-Amoxiclav therapy, pseudomembranous colitis may develop.

On the part of the skin: angioedema, rash, hives, rarely skin redness, dermatitis, Stevens-Johnson syndrome, toxic allergic dermatitis.

From the nervous system: rarely-excited state, anxiety, headache, dizziness, inadequate behavior, insomnia, convulsions, confusion, hyperactivity.

Anemia and other blood problems may also occur.

Dysfunction of the liver usually enlarges in elderly persons or in people who are prescribed long-term therapy with the drug.

On the part of the urinary system, you can sometimes observe an increase in the percentage of blood in the urine and inflammation of the kidney canals.

Sometimes there can be inflammation of the external genitalia and fever.

If you have therapy by the remedy for a long time, you may have candidiasis of the oral cavity.